Hoffenheim are the only team who have managed to beat Bayern Munich so far this season, having pulled off a 4-1 success on Matchday 2.
Sebastian Hoeneß’s men are without a Bundesliga win since that victory over Bayern, losing four and drawing one of their last five games.
TSG are unbeaten in their last five home encounters with VfB (W4 D1).
Andrej Kramaric has already hit half a dozen goals for Hoffenheim in the current Bundesliga season, and he did so in the opening three matches. The Croatian, who is the club’s record goalscorer in the top flight with 68 Bundesliga goals, has missed the last four fixtures after being infected with coronavirus.
A total of 25 players have already featured for TSG in the league this term. Together with Schalke 04, Hoffenheim have used the most players so far.
Hoffenheim’s tally of 52 points saw them finish in sixth place last season.
Former VfB man Sebastian Rudy is Hoffenheim’s record Bundesliga appearance maker with 231 outings in a blue shirt.