Saison:
| Platz | Spieler | Verein | Tore | |
|---|---|---|---|---|
| 1 | Grafite | VfL Wolfsburg | 28 | |
| 2 | Edin Dzeko | VfL Wolfsburg | 26 | |
| 3 | Mario Gomez | VfB Stuttgart | 24 | |
| 4 | Patrick Helmes | Bayer 04 Leverkusen | 21 | |
| 5 | Vedad Ibisevic | 1899 Hoffenheim | 18 | |
| 6 | Claudio Pizarro | Werder Bremen | 17 | |
| 7 | Milivoje Novakovic | 1.FC Köln | 16 | |
| 8 | Demba Ba | 1899 Hoffenheim | 14 | |
| 8 | Luca Toni | FC Bayern München | 14 | |
| 10 | Kevin Kuranyi | FC Schalke 04 | 13 | |
| 10 | Artur Wichniarek | Arminia Bielefeld | 13 | |
| 12 | Diego | Werder Bremen | 12 | |
| 12 | Alexander Frei | Borussia Dortmund | 12 | |
| 12 | Mladen Petric | Hamburger SV | 12 | |
| 12 | Stefan Kießling | Bayer 04 Leverkusen | 12 | |
| 16 | Andriy Voronin | Hertha BSC Berlin | 11 | |
| 17 | Ivica Olic | Hamburger SV | 10 | |
| 17 | Miroslav Klose | FC Bayern München | 10 | |
| 19 | Franck Ribery | FC Bayern München | 9 | |
| 19 | Dimitar Rangelov | FC Energie Cottbus | 9 | |
| 19 | Jefferson Farfan | FC Schalke 04 | 9 | |
| 19 | Sebastian Freis | Karlsruher SC | 9 | |
| 19 | Paolo Guerrero | Hamburger SV | 9 | |
| 19 | Stanislav Sestak | VfL Bochum | 9 | |
| 19 | Nikos Liberopoulos | Eintracht Frankfurt | 9 | |
| 19 | Hugo Almeida | Werder Bremen | 9 | |
| 27 | Jiri Stajner | Hannover 96 | 8 | |
| 27 | Sejad Salihovic | 1899 Hoffenheim | 8 | |
| 27 | Carlos Eduardo | 1899 Hoffenheim | 8 | |
| 30 | Cacau | VfB Stuttgart | 7 |
